Preheat Oven to 350 F and prepare 9 x 5 inch loaf pan. (slightly smaller pan works too)
Whisk together flour, baking powder, baking soda, and salt in a medium bowl. Set aside.
In bowl of stand mixer with paddle attachment, mix together olive oil, milk, and sugar until combined.
Add one egg at a time until incorporated.
Continue to mix on medium low adding vanilla, orange juice, and orange zest.
Next spoon in flour mixture.
Mix on medium until a smooth batter is formed. May need to scrape sides and bottom of bowl to incorporate all ingredients.
Pour cake batter into loaf pan.
Place on middle oven rack.
Bake 35-45 minutes or until toothpick inserted into the center comes out with only small crumbs.
Let cake cool on wire rack completely before removing from loaf pan and frosting.